You will get alot of different answers, each of us who own one will have our favorite.
First, consider your budget
second, if you have access to a quilt show, try out all the machines there.
third, any local dealer support?
fourth, the space you have available for set up.
I have the HQ 16 and love love it! I would upgrade to the Avante or Fusion if I had the space and the budget.