Melissa ....if I read you correctly the fabric pieces are already serged on at least three sides....as Boo mentioned the usage for these fabrics also is a consideration....however....if the fabrics say dry clean only....then sew them as though they were just that and then you can use a commercial dry cleaner product they have available for the average consumer and thereby save a few pennies. I believe you can get it at Wal-mart or any of the other chain stores. i have a few pieces myself and they will make a gorgeous duvet cover. The nice thing is with so many pieces you will be able to create a patchwork or applique piece unlike anything else available. good luck! If you decide to wash....cold water...gentle cycle...washing is to remove sizing and any dye leakage from the material....not usually a concern with upholstery material.