In the 1980s when finding 100% cotton was not as easy as now, I made a bed quilt for my son using some cotton and some polyester/cotton blends. He loved that quilt and 10 years later took it to college....boy dorm life is hard living for a quilt....they live on their beds, eat on them...etc. The point is that 4 years later, he came back with a quilt he wanted me to "fix". Batting was sticking out from 30 or 40 different places on the quilt. When I took a closer look, the places where the quilt disintegrated were all the poly/cotton fabrics. I couldn't salvage the quilt (I made him a replacement) but did immediately banish all of the poly/cotton fabric from my stash.