Yes...LOTS of baby "floor" quilts. I made and sold these for many years...have probably made close to a couple of hundred this way, all on the serger. They tend to lay flatter on the floor for a baby that is just starting to grab for things...less bunching under baby's chin. ;)
Another serger project I did was just a top....made for a table cloth so I wanted the back to be "finished".
Patti