My motto is: If it bothers you-change it. That is how I teach beginning quilters. They will leave things that I could never leave, but it isn't my quilt.
I am just fascinated by what bothers each of us. I made a pink and white quilt top like this yesterday afternoon. I have white strips beside each other and I didn't change it. Two colors side by side doesn't bother me, but a seam that doesn't meet will drive me crazy until I change it. Or a mistake in the pattern will drive me crazy until I change it, and many people leave them. There is a quilt hanging in a shop here that has a mistake. My eyes go to it every time and most people walk by and don't notice it. I have been known to take it(my quilt tops) off of the longarm frame and fix a mistake just because I have to.