I have a large craft table. First I find the center of the backing fabric and place a heavy pin in the exact center (on the right side of the fabric). Then I lay the backing, right side down on the table and and clamp or tape this fabric to the table. Make sure the fabric is taut (not tight, but taut).
Then lay the batting on top and spread it out. I often clamp the batting to the table, too. Lastly, center the quilttop on the backing-and-batting piece. Make sure the quilt top is facing up. Locate the center of the top and match it up with the pin on the right side of the backing fabric. This will ensure that your rabric is square on the back and batting. I don't clamp the top, but take care to spread it out evenly.
Once your fabric is secure in layers, start pinning from the center out. First pin the center. Then pin parallel and perpindicular across the center of the quilt, making sure the top is hand smoothed for taughtness and location (make your lines straight). After your cross lines are pinned, start pinning in each section. Make sure your pins are less than a hand print away from each other (you should feel at least one or two pins when you lay your hand flat).
Pin all the wayout to the border. You may find yoy need to adjust the border pins a bit when you get to the border, but that's okay.
When your whole quilt is pinned, remember to remove the lare pin on the underside of your quilt. It can damage a needle if sewn over accidently.
I machine quilt, so from here I quilt and take the pins out as I go.
I then sew much the same way. First I sew an anchor stitch the width and length of the quilt. Then I stitch whatever pattern in whatever sequence tht makes sense.
Hope this helps someone.