This is just a brainstorm that I came up with...may work, may not. I would open the picture with my computer's photo editing program and enlarge it as much as possible so that you can see the individual digital megapixels (like little squares of color). Print it out even if you have to do it in sections and then use these printouts as your foundation for paper piecing, matching small pieces of fabric to the colors of the enlarged photo. Then use threadpainting or various quilting patterns to enhance the elements of the quilt. There actually is a book that describes the process of converting digital photos to finished quilts-- Secrets of Digital Quilting--From Camera to Quilt: 8 Projects; 25 Techniques; Embellish with Paints, Inks & More [Paperback] by Lura Schwarz Smith and Kerby C. Smith. I have not read it but this may help explain the process better than I can.