I found this thread giving a great deal of information on threads, including Serger thread.
http://www.quilt.com/Bernina/Thread101.html
Opinions abound, but I think that Serger thread is to light weight. My serger takes 3-4 threads to work. Try breaking your favorite quilting thread, and then try breaking the serger thread. Over time some of the threads on your quilt may break with use. If you find no difference between your quilting thread and the serger thread, go for it.