The first one I made was quilted block by block as if each were a little quilt then I used sashing strips to put them all together to create a throw size.
The second one I made is a shaggy denim quilt where the arcs of circles (I used old blue jeans) are folded over to the front and squares of batting and fabric (I used hubby's outgrown work shirts) are tucked under the folds before they are stitched down making demim squares on the back of the quilt and a faux cathedral windwows or orange peel on the front. I laid out the squares in a Trip Around the World style and assembled the quilt in sections--9 or 12 patches as a time then in quarters for the final step. Pushing that much denim around is hard work on the shoulders but the technique will work with other, lighter fabrics. You can also sew 2 circles right sides together and cut a slit near where the fold will be to turn them right side out and slip a piece of batting in before sewing the circles together for a more finished look.