My mom had macular degeneration and laser surgery which destroyed the central part of her vision for seeing fine detail. We were able to get her a device called a Video Eye, expensive, but what a lifesaver. It helped her to do some reading, thread a needle, see her meds, etc. When the central vision is gone, peripheral vision, which can sense motion is still useful for many. To take advantage of it try not to focus on the thing you want to see, but scan from side to side as if it was "moving". As for sewing, I would suggest sticking to designs that made up of squares and strips rather than triangles and complex shapes. Your fingertips will become sensitive to sensing 1/4" seam allowances if you hand sew. If someone can bond applique pieces on to fabric for you, you might be able to overcast or buttonhole stitch around the edges by feel. Keep trying. Even if someone has to do some minor adjustments after you are done, they will treasure the time and effort you have put into your quilts. Don't hesitate to accept help from friends or relatives or a quilt group who can help you with some preparation work so you can continue with your sewing. Love, and good luck.