I use the teflon Supreme Slider and it really does make a difference in helping the quilt slide. Make sure you have plenty of table space to the left and to the back of your machine to take the weight of your quilt. Any time the weight of the quilt is dragging it down, your quilting will suffer.
I use safety pins and don't baste. If you're doing a fairly large quilting pattern, you can quilt around the pins without having to remove them. I've done a meandering pattern and just made a loop around the pins. I've done SID and made sure to put the pins in places that I knew I wouldn't be quilting. Not removing the pins saves a lot of time, but you have to be sure to stay well back from the pins so they don't catch on your darning foot.
Good luck!