Cuppi,
I once had a student with a partial hand due to birth defects, who quilted full sized quilts in her lap with no hoop or frame. Her work was absolutely amazing and cured me of thinking there had to be one way for everybody!
I have quilted many quilts on a floor frame, but now much prefer to lean back in my big club chair with a hoop propped against it's arm or my tucked up knee to handquilt. Feels much easier on my neck than sitting leaning forward over a frame.
Jan in VA