A doubled layer where the backing/binding comes over to the front of the quilt will last longer than a single layer.
This is true no matter what method of binding you use.
More layers means it will take more wear.
And if you wear out a single layer of self-binding, there is nothing to fall back on in years to come - it would have to have a new binding anyway.
If the quilt is not for long-term life, then it doesn't make a lot of difference.
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