The last one I did was a twin size coverlet type thing... I started in the middle and did a stipple type pattern and worked out in a bit of a spiral. I did a small section, rotated, did another small section, etc. and worked my way around. Starting in the middle helps keep everything together and there's less of a chance of puckering... any time I have jumped to the outside edge too soon I always regret it. Things shift and move and you don't notice it until it's waaaaayyyy too late!