I think the most important point is the 'why' - you quilt to relax, so to be neurotic about perfection would be counter-productive!
But everybody's different! I have some OCD tendencies - I have a child with severe autism and I recognize some of those characteristics in myself as well. So I pour my need to be picky and exact and ultra-focused into my quilts - instead of my messy, imperfect family members! It's much better to obsess over a seam until it lines up just right than it is to nag a loved one about something minor.
Quilting satisfies our souls in so many ways, and yet none of us are the same. Room for everybody, right?