Some home dec fabrics may be loosely woven or very thick/thin. I've used them in wall hangings by stabilizing with a thin iron-on interfacing. For a bed quilt that gets washed frequently, you may want to choose carefully. Hand quilting through some drapery fabrics can be difficult too.
I have fallen in love with a pattern or shiny color and used them, but they are going to wear differently. You can only clean a quilt in a method preferred by its most delicate components. Anything bed sized would be a huge pain in the neck to hand wash.