I quilt thru T shirt designs all the time and they hold up just fine. But tying is another good option. I would tie at the corners and maybe, if they are big blocks, somewhere else strategic within the blocks. If you reverse tie, IE: the tie is on the back, it won't be so noticeable. Depends on the look you are going for.
I lay out my tie quilts on the floor or a large table, sandwich them just like regular.
There are many ways to tie a quilt. I did a Google search and here are some sites to read thru.
http://www.google.com/#sclient=psy&h...289185d5cea093