We took the Alaska Cruise several years ago. It was great, but tiring having to be ready to go somewhere at 6 A.M.!
The best one was a river cruise on the Rhine and Danube rivers. It was a small ship, but luxurious. We got to know all the people and the scenery was spectacular. We stopped every day and took walking tours of the towns and cities like Nuremberg and Vienna and Cologne. There were a few bus trips. Fantastic!