After a very bad experience with literally melting/fusing a poly batting in the dryer, I now lay it out on a bed. I then spray it with a wrinkle-resist product, then smooth it out with my hands. I then turn on the ceiling fan and let it dry. This takes out some wrinkles, but doesn't really get out the major creases and poofs. I've only used bagged battings which are often rather wrinkled.
I think I will try the dryer again but will use a wet towel this time. In my first attempt, I had only sprayed a little water into the dryer.