You will need more than one fat quarter if you are making the large one. And you'll need more than one for the lining also. I would get about 4 to 6 fat quarters and you'll need some fuseable fleece also. Like the above poster said,, check the measirements of the pieces and yeppers,, you'll need more than one fat quarter for your new purse. good luck, Huggies, Fay