JUST ONE? no way...but if I had too it would probably be Grandmothers Flower Garden....only because it has always reminded me of my Grandmother who taught me to love gardening. Its not my favorite pattern but my favorite memory...someday I want to make an all red/white Triple Irish Chain..not my fav either but I saw one in a movie once and loved it...Trip Around The World is one of my favorite pattern but again not completely my final choice..Heck I have to have more than one favorite..one is not enough