She will only be able to concentrate for short periods of time, (My 28 year old son died 4 years ago, I know the feeling oh so well). You will need to keep it very simple (maybe 8" squares from his jeans). That would be something she could cut out on the days that she is able think clearly. Just have her keep cutting the squares until she has enough, then move to the next step. Skype is also a great way to keep in touch with her, on the days she wants to talk as well. I have Skype and have been teaching my sister to quilt this way for about 6 months (She lives 250 miles from me).