Well, are you hand piecing or machine-piecing?
How well can you gauge a 1/4" by eye?
If you're joining hex to hex, then it's all inset seams, "y" seams. You don't sew to the edge as you would if you were joining 2 squares or straight strips.
If it were me, I would mark a dozen, and sew them together (with either method) to get a sense of the where and why of starting and ending sewing on each line.
Then try a couple by eye. If you're comfortable enough, and the results are good enough, you can do it by eye.
If not, start making dots. Otherwise, it's going to be a wonky mess.