I have started using wool batting lately and love it, especially in larger quilts. It maintains it's loft and is soft and drapes beautifully. Poly batting will lose it's loft after a while leaving the quilt looking frumpy. Dream Wool (I think that's the name) can be quilted up to 10" apart. It's a bit more expensive (can't get it at Joann's with a 40% coupon) but when I have made a really nice quilt using good fabric it's worth it.