If someone gave me a handmade purse, quilt, afghan or whatever, regardless if the gift was my colors or not or if I would ever use it, I would give them a sincere thank you for the lovely gift. It means that they thought enough of you, to go through the expense and time and effort to make something unique. They could have just gone to the store or online and bought something that is mass produced and just like everyone else has-same color, same thing, etc.