I have made 430 completed quilts in the 10 years I have been quilting. While my guild owns a LA, I am too disabled to use it. I wore out a Bernina and now use a Janome. A great many of my quilts have been Queen sized, some king sized. I have won way more than my share of prizes in the process. Most of my quilting is free motion, so I do one smallish area at a time, then shift to another. It does take longer than using a LA, but it's mainly a matter of focus.
Recently, a friend has offered to LA my quilts. I am delighted to accept her help, but her quilting is a bit boring, so I have her do some parts, leaving the rest to me. Right now I am doing the background and borders on a king sized wedding quilt. There was much less pin basting to do this way. Another friend suggested using a board to roll the pin bastin on. It works very well for the bastng. (4.5"x1"x10')