Whatever you do the most keep in baskets you can get to easily, maybe even small projects next to your 'regular' chair to rest in. So if you want to do a lot of scrapbooking keep that handy all the time and pull the sewing machine out on weekends. Keep your cutting stuff handy during the week if you have time to work on projects. If quilting is going to be your thing, keep the machine handy and put the paint and scrapbooking away until the weekend.
And hey, what guy needs a walk in closet, make you son share the closet! Good luck, and don't give up, he will get back on his feet and you will get 'your space' back.