When I broke my arm, just before the vacation I was to sew, sew, to finish an important project, I had Mom come over and do the cutting. With a cast on my right arm, I was able to maneuver the fabric where it needed to go -- if you can find an accurate cutter, you are good to go.
I should mention the project was my DD's Champion Irish Dancing Dress with heavy embroidery and machine applique. Not quite a quilt, but the cutting was the thing.