I had one of my cats spray/pee on one of my quilts. I figured it was ruined anyway so I washed it real well (it had dried by time I realized it) with regular soap. It came out just fine and obviously it all came out because there are 5 other cats here and no one else ever peed on it. As anyone with cats know, they can't help but pee on something they smell from another cat- at least that has been my experience. Since I knew it was there and it bothered me, I washed it a couple more times and we have never had any other problems and no more peeing- thank goodness!