I don't find skeleton/goth type fabrics odd and I don't find knitting or quilting themed fabric odd, but I find it odd they would combine the two themes into one fabric print. Most younger people (and I say that as lightly as possible since I'm only 30) who would like skeleton stuff, aren't going to like sewing related stuff on the same fabric. And most people who like sewing stuff, are probably not going to want skulls all over it too.
Maybe it's supposed to symbolize knitting and quilting will be the death of you?
I don't know. What I do know is I'm as likely to buy it as I am that horrible pregnancy fabric you posted last year sometime. The one that said "knocked up" all over it. Blah. :P