I tried both readers and decided on the Kindle. Here are the reasons behind my personal choice:
1. I liked the controls on the Kindle better, they felt more intuitive to me
2. I didn't like the backlighting as I feel it causes eye strain for me. I use a book light, just like I would with a real book when I read my Kindle at night
3. I have had some less than favorable experiences with the Customer Service 800# at Barnes and Noble but have had nothing but great experiences with Amazon Customer Service.
4. I had two different friends who broke their Kindles, not the product's fault, and both were replaced with new Kindles before they even sent their broken ones back because Amazon insisted they shouldn't have a lull in their ability to use the product.
5. With Calibre (free software for converting ebooks and putting them on your reader) and an iphone, (I have access to nook books on my iphone should I choose) I have found plenty of books. However, I have yet to use this feature much as I've never had trouble finding books.