this is my vote also. You might lose the overalll beauty of the piece. Not that one block wonders aren't beautiful, I would pick a fabric not quite as pretty for OBW.
Originally Posted by PatriceJ
i would leave that fabric uncut and build around it.
not only is it beeeuooooteeefaminous, look at all the possibilities it offers for practicing hand or machine quiltings of all sorts. :-)