I still quilt by hand as can not get the hang of MQ. When I do a large quilt I find for me it is daunting to quilt the whole thing as one piece, so I do a section at a time then sew them together. I think it is called lap quilting or maybe QAYG. Often I use a different fabric for the backing on each section, or stray blocks. Then it kinda makes my quilts reversible. Only downfall is there is more hand stitching to be done putting back together but I find I get more done in smaller pieces.