I use patterns and usually follow the directions to the end. I am always afraid if I do not my quilt will not come out right. I am always amazed by people that do not use patterns. They think out of the box.
Recently I ventured out of my very comfortable box and made some doll quilts. I thought if I goofed up it was only a little quilt. I was surprised that they actually came out pretty well. But try this on a large scale? I don't think so.