I hand quilt all my special quilts. Baby quilts are usually machine quilted or tie tacked as are the charity quilts. I just cannot use all the time it takes for hand quilting on a baby quilt.
Anyway. I have quilted all the way up to a queen on my little lap frame. It's a 12" hoop, but it gives me almost 11" to work with at a time. Since I am a full time mom and I used to work full time, it would take me a considerable amount of time, only stitching in the evenings, to get them quilted. I used both spray and pin basting. I still don't completely trust spray basting to stay put. I spray first, then pin. I've never had a problem with my needles in it. Start in the center and work your way out.
I must say that when you are quilting that big of a project in your lap, you want to have the bulk or weight of the quilt anywhere but on the frame. It could damage the frame (don't ask me how I know). I quilted my dh's quilt right in front of him. He didn't know it was for him until he opened it. Anyway, I mark as I go. I painstakenly marked a huge quilt with a pretty purple pen once. By the time I was done, have the markings were already gone. I had no idea disappearing ink even existed! I started using a chalk pencil on my last project and loved it. I've now graduated to those resin mechanical pencils. Marking is a dream!