I have used cross stitch in wall hangings. See pictures below and my avatar. I think the motifs should hold up pretty well in a quilt, especially if you bond some interfacing to the back to help secure the stitches. You can easily use the small ones for greeting cards . . . add them to a bag . . . there are so many possibilities. Don't discard them!
Greeting Card
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Wall Hanging
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Wall Hanging
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