I like Quilter's Dream Request or Select for hand quilting. I know a lot of people like Warm and Natural, but I found it hard to needle, and the quilt was very heavy when done. That's just my opinion, though, and it may work very well for you and be just what you want for your quilt! I also have used Hancock Fabrics own brand (sorry, I can't remember the name) and found it very easy to needle. I prefer a cotton or cotton blend regardless of the brand (although I've heard wool is a dream to quilt).