My first quilt, a queen, had 4" squares, it's my avatar. I used a bunch of different batiks, so I was anxious to see what fabric combination each block would produce. At first. 250+ blocks is a lot! When I ran out of steam, I decided to to 20 blocks a day. This worked for me. I guess I was used to creating lots of duplicate items. I used to make wedding invitations and favors. Make 400 wedding favors in your least favorite colors and it's great practice for quilting. ;-)