I often use Kona cotton solids (100% cotton broadcloth) in quilts, sometimes entirely, and have no problems at all. I do not hand quilt, but even with very close seams on a recent project (i.e., quarter inch apart) my longarmer had no trouble at all. With seams that close on a pieced top, or with thick intersections, you may want to use a walking foot so as not to 'lag' when crossing them. I notice no difference at all in hand stitching the bindings.