One I have done, goes together quickly, looks like you spend more time.
Pretty fabrics
Cut large florals into 10 or 12" squares.(You can use any size square that you choose) since your print is larger, larger squares will allow it to show. Set on point. frame with smaller prints or solids. I do the setting on point by sewing two blocks together all around. Draw an x corner to corner and cut on outside fabric.. press open. sew blocks together and add a border.
For wheelchair bound people, I add 3 ties. 2 on top the third lower to anchor to chair. That way it will not slide off.
Good luck. Enjoy grandma.
Show us a pic after you finish regardless of design.