Not sure what kind of vacay you want. We had fun here a couple of years ago:
http://www.trails.com/rentals/proper...20St.%20Joe_FL
The Cape is very laid back and there isn't a lot going on. But that was what we were looking for! And we ate our weight in fresh oysters and shrimp! Appalachiccola is less than an hour's drive and fun to explore too.