I love my Janome machine. I have a Janome 300E machine that was given to me by a friend, but have not used it yet.
One thing that you need to consider is the amount of memory available for the design, I think the Janome is limited..
Also, make sure you dont need to load the designs onto a proprietary card..in other words, make sure it has a usb port for designs.
Thats my very limited amount of opinion.. and it comes from shopping around for a machine..