I made a quilt for a girl's graduation gift. The hankies were her deceased grandmothers so it meant a lot to her. Not all the hankies were the same size, so I cut muslin squares 1/2" larger than the largest hanky and then machine stitched each hanky to a square near the hanky hem.(center the smaller ones). (If you have a fancy stitch on your machine, you could stitch them to the muslin with colored thread) Sew the squares together with a narrow sashing and add a border, batting and backing. I tied the quilt rather than actually quilting it, with one knot in the center and one at each corner. (Hankies can be quite thin fabric, so the muslin strengthens the whole thing)