I used different sides to my blocks - all were purposefully made wonky: triangles, 4 sided, 5 sided, and 6 sided. I loved the variety the different sided beginnings made in the overall effect. I did foundation piecing so I didn't overgrow the block too much. And I did go in only one direction around the first piece and subsequent pieces.
It was fun and a great way to use of scraps.
ali