I repaired one of my girlfriend's quilts that her grand had made for her. It was so worn thru the fabric & batting & backing. Luckily it near an end. So I took the binding off that end & around the sides. Then cut off the quilt to where the holes were ( it was probably half a block) & sewed the binding back on. It was a long quilt so was very usable afterwards. Hopefully the hole in yours is towards an end. Being you're in a wheelchair, it might be an easier size for you. Hope this helps & good luck.