I've used Crayola washable markers three times and had no trouble, though I read too much and all 3 times I've gotten up in the middle of the night to wash the quilt, even before the binding was attached. I scrub it with SHOUT (the deoderant-stick kind) before putting it in the washer - maybe I don't need to, but it makes me feel more confident. They say DON"T USE THE YELLOW