I have started quilting my large quilts on my Janome 6600. I ma getting better each time. I am almost finished w/a Full size bed quilt and I am super happy with it. I have several Full size quilts to do and a couple of King size. I found that if I set up a table to the left of my machine and a table behind my machine I have alot of flat surface for my quilt to lay on and it is not dragging. I don't roll it, I just scrunch and get to the part I want to quilt and work on it and then shift.
When I FMQ, I set the tension to 7 and go from there. I haven't had any problems w/eyelashes since - UNLESS I make a curve way too fast. I have started slowing down my hands and the machine and that also seems to help. Faster is not always better!