I haven't done one of my own quilts in awhile....but I use to use dream puff all the time..I love it. I have also doubled up and used Hobbs poly down several times.
Here is a post where I doubled up
http://www.quiltingboard.com/t-95504-1.htm
Dream puff isn't as poofy as this.....I love the poofy look myself....but I know not everyone does.
I also quilt on a long arm...I can't imagine doubling up and pushing it through my domestic machine...that is for someone who has the patience of a saint..LOL....just my two cents worth.