Just to stretch the thought here. I have quilted my own and customer quilts with a double batting, cotton/ wool, wool being on top. You have to remember how warm Poly is... very warm! A double cotton gives you more texture also. I have done trapunto also, that is with Poly cut away in an area to give more definition to a quilt. Great for an art quilt.
If you want to use the quilt, I always prefer a natural fiber.