3 years ago I machine quilted a quilt top my grandmother made - probably late 1930's or early 1940's. It had been folded up in various drawers for most of its life and was in pretty good condition. I don't think it was hand sewn, though, I think my grandmother used a sewing machine. The fabrics are definitely 1930's , and look like scraps from dresses and shirts her family wore at one time.
Bottom line is that it turned out fine. I now store it on top of the bed in the guest room, but underneath a 'store bought' quilt that I've had for over 20 years.
My youngest daughter has claimed "Grandma's quilt" when I go to my reward. Meantime, my 'grands' use it when they visit. Even old quilts need love!
I confess that I knew almost nothing about caring for aged fabrics when I machine quilted it, or maybe I would have made a different decision. Sometimes ignorance is bliss.